Distribution of CYP2C9 and VKORC1 Gene Polymorphisms in Healthy Macedonian Male Population

نویسندگان

  • Krume Jakjovski
  • Nikola Labachevski
  • Aleksandar Petlichkovski
  • Aleksandar Senev
  • Jasmina Trojacanec
  • Emilija Atanasovska
  • Elena Kostova
  • Mirko Spiroski
چکیده

Material and Methods: Blood samples were collected after signing written consent, DNA was isolated from peripheral blood, and CYP2C9 and VKORC1 genes were typed (n=124). Genotyping was performed by commercially available kits (GeneID GmbH, Strassberg, Germany, AID Diagnostica), based on the method of polymerase chain reaction with a subsequent hybridization. The population genetics analysis package, PyPop ver. 0.6.0, was used for analysis of the data.

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تاریخ انتشار 2013